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2-minute Test

The Concussion
Game-Changer

Safe. Simple. Science-Driven.

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All you need is the MySafePass Test Card and a Cell Phone

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Rapid, objective, mobile concussion screening

Fast Results
Under 2 minutes

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FDA Registered
Medically validated

Objective Testing
Clear pass/fail outcome

Challenge

The Challenge: Concussions

1.6 - 3.8 million

Concussions

An estimated 1.6 - 3.8 million sports-related concussions occur annually in the United States.

50 - 60 %

​undiagnosed

Missed Assessments

Up to 50-60% of concussions go undiagnosed using traditional assessments

5 X

higher risk

Long-Term Impact

People with undiagnosed concussions face up to 5x higher risk of serious brain injury if returned to play too soon.

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The Problem

  • Concussions are prevalent in sports but difficult to diagnose on the sideline, putting athletes at serious risk.

Current Limitations

  • Affected by player adrenaline and motivation to return to play 

  • Traditional assessments (eg. SCAT5) are subjective and time-consuming

  • Low sensitivity misses subtle brain injuries

"The 2-minute MSP smell test of olfactory function would be a game-changer for our understanding of repetitive head injuries."

~ ScienceDirect.com

Solution

The Solution: MSP Olfactory Concussion Testing

Revolutionary Approach

MySafePass (MSP) delivers an innovative olfactory test that objectively detects concussions by measuring changes in the brain's smell processing pathways.

Proven Science

The olfactory system is directly connected to brain regions vulnerable to concussion damage. When injury occurs, smell processing is immediately affected—often before other symptoms appear.

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01

Rapid Assessment

Complete test in UNDER 2 MINUTES, allowing for immediate sideline decisions

02

Objective Results

Clear pass/fail metrics eliminate guesswork and subjective interpretation

03

Medical Credibility

FDA Class II registered medical device with peer-reviewed scientific validation

MySafePass offers what current protocols lack. A fast, objective, and non-invasive assessment that can be administered by any medical staff or coach, providing immediate guidance when player safety is on the line.

Science

Real Science: Why Smell Testing Works

Brain-Nose Connection

The olfactory system is directly linked to the brain's frontal lobe and other regions highly vulnerable to concussion damage.

How Concussions Impact Smell

  • Sudden head impact creates shearing forces that disrupt olfactory neural pathways

  • Damage to the cribriform plate can affect smell processing 

  • Changes can be detected immediately, even when other symptoms are absent

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Olfactory neural pathways connecting nasal cavity to brain

01

Research Evidence

Up to 68%of traumatic brain injury patients show measurable olfactory dysfunction

02

Early Detection

Olfactory testing can detect concussion Olfactory testing can detect concussion even when other assessments appear normal

03

Elite Athlete Studies

Former NFL players showed significantly worse olfactory test scores compared to controls, correlating with mood and cognitive symptoms

04

CTE Connection

Olfactory dysfunction is linked to tau protein accumulation in brain regions affected by chronic traumatic encephalopathy (CTE) 

"It's long been known that people who suffer a major concussion can lose their sense of smell temporarily. Now scientists have found that's true even for people who get a minor concussion."

~ ScienceDirect (2023)

Protocol

How It Works: 5-Step Sideline Protocol

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Easy Implementation for Every Team. Seamlessly integrate MySafePass into your existing concussion protocols with minimal disruption and maximum impact.

All you need is the MySafePass Test Card and a Cell Phone

01

Baseline Testing

Athletes perform the MSP test during pre-season physicals to establish their normal olfactory function.

02

Suspect Head Injury

Remove player from activity and bring to the sideline. Medical staff initiates standard assessment protocol.

03

First Test Fail

If player fails the 1-minute MSP smell test, immediately perform a second test for verification.

04

Second Test Fail

Player who fails two consecutive MSP tests should be removed from play -high risk of concussion.

05

Documentation & Follow-up

Record all test results. For pass/fail scenarios, complete your standard assessment protocol and document all findings.

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Test Card

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Real-Time Results

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Clear Pass/Fail

Pro Tip: Keep MSP test kits easily accessible in your medical bag and train all medical staff on proper administration.

Contact

Next Steps: Protect Everyone Today

Start Protecting Now - Medical professionals available for consultation.

Schedule a Demo

Book a live or web meeting for a full overview and Q&A session with our experts.

Request Sample Kits

Get sample MSP tests for your organization and trainers to experience.

Integrate the Protocol

We provide complete guidance to help you incorporate MSP into your official concussion assessment procedures.

Learn More

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Scientific Citations Support Olfactory Testing in Concussion Protocol

1. Evidence for Olfactory Dysfunction Following TBI/Concussion

Schofield, P.W., Moore, T.M., & Gardner, A. (2014)."Traumatic brain injury and olfaction: a systematic review."Frontiers in Neurology, 5, 5.Link

  • Key Finding: Systematic review of 25 studies found olfactory dysfunction is common after TBI, with prevalence ranging from 20-68% depending on injury severity

  • Citation Count: 137

  • Relevance: Establishes that olfactory testing can detect TBI-related dysfunction that often goes unrecognized

Alosco, M.L., et al. (2017)."Olfactory function and associated clinical correlates in former national football league players."Journal of Neurotrauma, 34(4), 772-778.PMC Link

  • Key Finding: Former NFL players showed significantly worse Brief Smell Identification Test (B-SIT) scores compared to controls; worse olfaction correlated with mood symptoms and executive dysfunction

  • Citation Count: 55 citations

  • Relevance: Demonstrates link between repetitive head impacts and long-term olfactory dysfunction

 

2. Current Concussion Protocols Lack Olfactory Testing

Research Gap Evidence: Current standard concussion assessment tools (SCAT5, ImPACT) do not include olfactory function testing despite scientific evidence supporting its clinical utility.

Lecuyer Giguère, F., et al. (2019)."Olfactory, cognitive and affective dysfunction assessed 24 hours and one year after a mild Traumatic Brain Injury (mTBI)."Brain Injury, 33(8), 1067-1077.

  • Key Finding: Olfactory dysfunction present 24 hours post-mTBIand persisted at one year; correlated with cognitive and mood symptoms

  • Citation Count: 32 citations

  • Relevance: Shows olfactory testing could be valuable in acute concussion assessment

 

3. Olfactory Testing as Early Marker for CTE-Related Pathology

Frank, M.E. & Hettinger, T.P. (2018)."Tracking traumatic head injuries with the chemical senses."World Journal of Otorhinolaryngology-Head and Neck Surgery, 4(1), 51-55.

  • Key Quote:"A test of olfactory function and CTE in real time would be a 'game-changer' in our understanding of repetitive head injuries"

  • Citation Count: 5 citations

  • Relevance: Directly supports the statement's claim about potential for real-time CTE assessment

Yoon, Y., et al. (2022)."Increases of Phosphorylated Tau (Ser202/Thr205) in the Olfactory Regions Are Associated with Impaired EEG and Olfactory Behavior in Traumatic Brain Injury Mice."Biomedicines, 10(4), 865.PMC Link

  • Key Finding: Phosphorylated tau accumulation in olfactory regions correlates with olfactory dysfunction after TBI

  • Citation Count: 5 citations

  • Relevance: Provides mechanistic link between CTE pathology (tau) and olfactory dysfunction

4. Brief, Practical Testing Available

Doty, R.L. (1995).The Brief Smell Identification Test (B-SIT) -standardized 12-item test that can be completed in 5-10 minutes

  • Clinical Utility: Validated, reliable, cost-effective screening tool

  • Relevance: Supports feasibility of incorporating smell testing into concussion protocols

5. Olfactory Dysfunction Correlates with Cognitive/Behavioral Issues

Xydakis, M.S., et al. (2015)."Olfactory impairment and traumatic brain injury in blast-injured combat troops: a cohort study."Neurology, 84(15), 1559-1567.

  • Key Finding: Olfactory impairment was the most common neurological deficit in veterans with combat-related mTBI

  • Citation Count: 48 citations

  • Relevance: Demonstrates olfactory testing's sensitivity in detecting TBI-related neurological changes

 

6. Tau Pathology and Olfactory System Connection

Recent studies (2024-2025)have established strong links between tau protein accumulation and olfactory dysfunction:

  • Nature (2024): "Tau propagation in brain olfactory circuits is associated with odor identification deficits"

  • Wiley (2024): "Olfactory dysfunction as potential biomarker in neurodegenerative diseases"

 

Summary of Supporting Evidence:

Prevalence: ~68% of TBI patients show olfactory dysfunction

Sensitivity: Often detects deficits when other tests appear normal

Practicality: MSP offers a 1-2 minutePass/Fail assessment

Correlation: Links to cognitive, mood, and executive dysfunction

Pathological basis: Associated with tau accumulation in olfactory regions

Longitudinal tracking: Can monitor changes over time

Gap in protocols: Current concussion assessments (SCAT5, ImPACT) don't include olfactory testing

The scientific literature strongly supports the statement that olfactory function testing should be part of concussion protocols and could serve as a valuable tool for tracking CTE-related changes over time, yet it remains surprisingly absent from current standard protocols.

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